Integrated cardiac safety assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance - Turner, J. Rick.; Durham, Todd A. (Hoboken, N.J. : John Wiley & Sons, 2009)
The importance of cardiac safety assessments -- The biological basis of adverse drug reactions -- Cardiac structure and function -- Cardiac pathophysiology and disease -- Drug discovery and drug design -- Nonclinical development -- The thorough QT/QTc trial -- General safety assessments -- Therapeutic use trials and meta-analyses -- Assessment methodologies in nonexperimental postmarketing surveillance -- Postmarketing proarrhythmic cardiac safety assessments -- Generalized cardiac safety -- Medication errors, adherence, and concordance -- Future directions in drug safety.
Includes bibliographical references (p. 397-455) and index.
Description based on metadata supplied by the publisher and other sources.
Electronic reproduction. Santa Fe, Arg.: elibro, 2021. Available via World Wide Web. Access may be limited to eLibro affiliated libraries.
Keywords: Cardiovascular toxicology; Heart -- Effect of drugs on; Drugs -- Side effects -- Testing; Drugs -- Safety measures; Electronic books